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Kor J Aesthet Cosmetol 2012;10(4): 961-968. |
| 호장근 추출물의 미백효과 및 자외선 차단효과 분석 |
| 김민정, 유민정 |
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| Inhibition of Melanogenesis and Anti-UV properties Reynoutria elliptica |
| Min-jung Kim, Min-Jeong Ryu |
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| ABSTRACT |
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Reynoutria elliptica is Asian as traditional herbal medication. In this study, we examined the Inhibition of
melanogensis and anti-UV properties ethanol extract of R. elliptica. Total polyphenols and flavonoids contents
of R. elliptica, the result was respectively 209.2±1.2, 83.4±2.0 mg/g. Electron-donating ability of ethanol extract
of R. elliptica was in 400 ㎍/㎖ as 92.92±1.51%. Tyrosinase have suppress effect in a dose dependent. UVblocking
effect was also showed a strong UV absorption in the range of UV-A(350-370 ㎚). In addition we
tested tyrosinase inhibition activity and melanin contents on SK-MEL-2. Tyrosinase was inhibited to 40% at
the dose of 20 ㎍/㎖ and melanogenesis was inhibited was 30%. Overall, our results indicate that R.elliptica
extract showed that the α-MSH-mediated upregulation of tyrosinase activity and melanogenesis were inhibited
in the extract does dependent manner in Sk-MEL-2 cells. Hence, R. elliptica extract could be applied as a type
of dermatological whitening and anti-UV agent in skin care products. |
| Key words:
Anti-UV, SK-MEL-2, Tyrosinase, Melanin |
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