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Kor J Aesthet Cosmetol > Volume 8(2); 2010 > Article
Kor J Aesthet Cosmetol 2010;8(2): 139-148.
노화과정에서 저근육형 비만에 대한 이론적 연구
노재경
A Study of the Sarcopenic obesity in aging
Jae-Kyung No
ABSTRACT
Sarcopenia is defined as the age-related loss of skeletal muscle mass and strength. Sarcopenic obesity is the combination of sarcopenia with decreased bone mass, i.e., osteopenia, is related directly to increased risk of falls and fractures in the elderly. Sarcopenic obesity may have an even greater negative impact on health in the elderly than either sarcopenia or obesity alone. Obesity in aging is a major risk factor for chronic diseases due to its proinflammatory nature that underlies major age-related such as type Ⅱ diabetes and cardiovascular disease. The most crucial fact in sarcopenia is that inflammatory cytokines produced by adipose tissue, especially visceral fat accelerate muscle catabolism, thus playing the causative role in the age-related muscle loss. Recent advances in our understanding on the prevention of the aging and age-related pathological processes highlight the importance of sarcopenia obesity Thus, a better understanding of sarcopenic obesity will provide scientific basis and justification for the doable interventions that may lead to successful aging.
Key words: Sarcopenic Obesity, Sarcopenia, Obesity, Aging, Inflammation
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