Asian J Beauty Cosmetol. 2011; 9: 0.
A Study on Antimicrobial Effects of Silver-Alginate on Propionibacterium acnes
ABSTRACT
This study conducted low-molecularization of alginate to maximize antimicrobial effects and examined
antimicrobial effects silver-alginate which substituted Ag+ for silver(Ag, organic antimicrobial)
on Propionibacterium acnes.
Antimicrobial effects of silver-alginate which was substituted by Ag+ in low-molecular alginate
on P. acnes was identified by MIC. As a result, it was found that low-molecular alginate(MIC =
10,000 ㎍/㎖) and silver-alginate(MIC = 200 ㎍/㎖) had more excellent antimicrobial than lavender oil
and tea tree oil which are well known for excellent antimicrobial(MIC = 20,000 ㎍/㎖).
Concentration according to culture time of P. acnes was examined. As a result, concentration of
silver-alginate was 0.10, 0.15, 0.21, 0.31, 0.48, and 1.01 by culture time. It indicates that it significantly
inhibited the growth of P. acnes compared with the control group. Also, MIC and concentration
according to culture time was measured in P. acne of alginate paste made of silver-alginate
solution, and antimicrobial persistence was confirmed. acnes concentration, suggesting more excellent
antimicrobial and persistent antimicrobial.
Keywords :
silver-alginate, P. acnes, antimicrobial , low-molecularization, alginate paste
